Yes, it’s common for dogs to feel tired after receiving a rabies shot. This mild fatigue is typically a normal immune response and should pass within a couple of days. If symptoms persist or worsen, consult a veterinarian.
What Is the Rabies Vaccine and Why Do Dogs Need It?

The rabies vaccine is a vital component of canine preventive care. Designed to protect against the fatal rabies virus, this shot is legally mandated in many regions due to the public health risks associated with rabies transmission. Rabies is almost always deadly once symptoms appear—both in animals and humans.
When a dog receives the rabies vaccine, it stimulates the immune system to recognise and fight off the rabies virus if the dog is ever exposed in the future. It’s not just about your dog—it’s about protecting the broader community.
Is It Normal for Dogs to Feel Tired After a Rabies Vaccine?

Absolutely. Many dogs experience mild lethargy or sleepiness following vaccination. This is not a sign of something wrong—it’s actually a sign that the immune system is doing its job.
A dog’s body reacts to the vaccine by building antibodies. This immune process can drain energy temporarily, making your dog appear sluggish or less active than usual.
What Causes Lethargy or Tiredness After a Rabies Shot?

Fatigue after a rabies vaccine is caused by:
- Immune response activation: The body shifts energy toward building immunity.
- Mild inflammation: As the immune system ramps up, temporary inflammation can create low-grade discomfort.
- Cellular energy demand: Resources are redirected internally, often making your dog less energetic.
This type of post-vaccine fatigue is typically short-lived and shouldn’t be cause for concern.
Common Side Effects of the Rabies Shot in Dogs

Most side effects are mild and resolve within 24 to 48 hours. They may include:
Tiredness or fatigue
Mild fever
Decreased appetite
Tenderness, soreness, or slight swelling at the injection site
General sleepiness or reduced activity
Mild irritability or restlessness
Headache
Nausea and vomiting (throwing up)
Abdominal discomfort or stomach pain
Dizziness
Muscle aches or joint pain
Swollen lymph nodes
Rash
Vomiting and nausea are reported in a small percentage of individuals receiving the rabies vaccine. These symptoms are generally mild and short-lived. In rare cases, especially after booster doses, more noticeable symptoms such as joint pain, swelling, fever, and vomiting may appear between 2 to 21 days after vaccination.
How Long Will My Dog Be Tired After a Rabies Shot?

On average, dogs feel tired for 24 to 48 hours after the shot.
Day-by-day symptom expectations:
- Day 1: Fatigue, possible mild fever, soreness
- Day 2: Symptoms begin to fade
- Day 3: Most dogs return to normal
If your dog still seems unusually tired by day three or four, or if symptoms intensify, contact a veterinarian.
Do Age, Size, or Breed Affect How Dogs React?

Yes, reactions to the rabies vaccine can vary by age, size, and breed:
- Puppies may show stronger fatigue since their systems are still developing.
- Senior dogs may take longer to recover due to slower immune responses.
- Small breeds can sometimes exhibit stronger side effects because of their body weight relative to the vaccine dose.
- Breed sensitivity: Breeds like Dachshunds, Pugs, or Chihuahuas may be more prone to post-vaccine lethargy.
These aren’t hard rules, but trends noticed by many pet owners and some veterinary professionals.
When Should You Be Concerned?

While most dogs bounce back quickly, watch out for more serious symptoms such as:
- Vomiting or diarrhea
- Facial swelling
- Difficulty breathing
- Unresponsiveness or collapse
- Hives or severe itching
These may indicate an allergic reaction or anaphylaxis. Seek emergency veterinary care if you observe any of these signs.
Post-Vaccine Care: What You Can Do

Caring for your dog after a rabies shot is simple, but effective:
- Keep your dog indoors in a calm, stress-free environment
- Offer fresh water frequently
- Avoid strenuous activity or long walks
- Don’t force your dog to eat if their appetite is low
- Gently check the injection site for swelling or sensitivity
Create a cosy rest space so your dog can nap without disturbances.
Can You Prevent Rabies Vaccine Side Effects?

While not all side effects can be prevented, you can minimise risks:
- Ensure your dog is healthy before the shot—don’t vaccinate a sick dog
- Discuss pre-vaccine antihistamines with your vet if your dog has a history of reactions
- Stick to core vaccines only unless others are necessary
- Space out vaccines when possible instead of doing multiple at once
Planning ahead can make the process smoother and easier for your pet.